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Tissue repair: mechanisms are not treatment proof

Tendon and muscle repair involve inflammation, vascular signaling, extracellular-matrix remodeling and mechanical loading. Reviews discuss factors such as VEGF and IGF-1 within these processes, but mechanistic plausibility does not prove that an unapproved peptide improves recovery in people. Evidence must distinguish cells, animals and humans and must identify the intervention actually tested. The cattle study previously cited in the source set was excluded as irrelevant to human peptide recovery.

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Tissue repair: mechanisms are not treatment proof

Tendon and muscle repair involve inflammation, vascular signaling, extracellular-matrix remodeling and mechanical loading. Reviews discuss factors such as VEGF and IGF-1 within these processes, but mechanistic plausibility does not prove that an unapproved peptide improves recovery in people. Evidence must distinguish cells, animals and humans and must identify the intervention actually tested. The cattle study previously cited in the source set was excluded as irrelevant to human peptide recovery.

Evidence identifiers

Informational content for research. This material is educational and intended for laboratory research contexts. It is not medical advice, a prescription, a clinical protocol, or a guarantee of outcome.

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